Simply dial the local access number you've selected and "VoxGirl" will talk you through the voice-activated dialing process. At VoxGirl's prompt, say the name of the contact you wish to speak with, followed by which number you'd like MOBIVOX to dial (Skype, cell, home, etc). When I said, "Joe, Skype," the system confirmed my choice, gave me the option of canceling, then connected me immediately.